best vitamin b6 and b12 supplements

Though it’s one of the most common brands you’ll find at a brick and mortar retailer, Nature’s Way actually makes a pretty solid vitamin B6 supplement. Their study involved matching patients with confirmed cardiovascular disease to healthy controls who were otherwise similar. Vitamin B6, also known as pyridoxine, is a B-complex vitamin involved in over 150 enzyme reactions. Although product recommendations are only our opinions, this research-backed page has been fact-checked and reviewed by a certified nutritionalist or health specialist. Those who have a Vitamin B6 deficiency tend to be those who consume a large amount of alcohol, pregnant women, breastfeeding women, those who are obese, children, the elderly, or those who take medication that causes a deficiency. Everyone has a different preference when it comes to supplements and which ones they prefer. All of Nordic Naturals’ supplements are non-GMO, as well as gluten- and dairy-free, and do not contain artificial colors, flavors, or preservatives. In addition to cardiovascular and cognitive health, it appears that vitamin B6 is critical for the integrity of the DNA in your cells, too. B complex, which contains the spectrum of B vitamins, will keep your body strong while…. The good news about trying to find a supplement that contains both Vitamin B6 and B12 is that it’s not hard. If you’re taking a combination of Hexalen and Cisplatin, the adverse effects are worse. Taking Vitamin B6 with Altretamine, which is a chemotherapy drug, can reduce the effectiveness of the drug. 10 Best B12 Supplements December 2020 Results are Based on. If you’re looking for a high quality B complex supplement, try out one of the products listed above. At 200 mg per capsule, its dosage is too high for regular use, so this supplement should be reserved for people who need to take beyond the normal recommended upper limit on B6 intake. Diabetics should also proceed with caution as it may interact with some of their medications negatively. Vegans are at risk of developing a deficiency in certain B vitamins, including vitamin B12, as these nutrients are most concentrated in animal-based foods (15). NSF is an independent organization that tests for supplement quality. Taking 50 to 100mg per day, combined with 200mg of magnesium, could substantially help. Research establishing this link was published in 1998 in the journal Circulation by a team of doctors at the Cleveland Clinic (2). Vitamin B6 deficiency is surprisingly common but difficult to detect, particularly in older adults, so ensuring that you get enough of this critical vitamin is very important if you want your body in good health. Moreover, we have included a brief description of each product to help you compare them. For this reason, it’s important to keep them out of reach of children to prevent accidental ingestion. Vitamin B6 can help protect your DNA from damage. What happens if I take too much Vitamin B6? B vitamins are relatively safe, even when taken in very high doses. Our top choice, Pure Encapsulations, went above and beyond to provide a more bioavailable form of vitamin B6 – P5P. However, they do not have the same effects on your health. Low vitamin B6 is, in turn, a cause of high levels of homocysteine (the same compound that is targeted by, Research establishing this link was published in 1998 in the journal Circulation by a team of doctors at the Cleveland Clinic (. The company exploits the fact that “vitamin B6” isn’t one distinct chemical; it’s a category of related compounds. Blackmores, Vitamin B12 (tablets) Nature’s Own, Vitamin B12 (tablets) Vitamin B12 has many benefits to our health and body. With lower dosages, you are better able to tailor your dose to fit your specific needs. If you’re looking for the best vitamin B6 supplements to buy this year, then you’ve come to the right place. It is also often used in conduction with other vitamins to facilitate proper body functioning. The link between vitamin B6 and cardiovascular health is a compound called homocysteine. There are eight B vitamins that all play vital roles in your body. It’s a metabolite in your blood, and high levels of this compound have been linked to an increased risk for heart disease and stroke. Deficiencies in both vitamins can result in anemia and confusion, but a B12 deficiency can lead to dementia and loss of your sense of touch. It delivers 100 mg per capsule, and the supplement design is pretty clean. That was the conclusion of a study published in the American Journal of Clinical Nutrition by researchers at Tufts University (4). Later research confirmed this association in a 14-year study of female nurses described in the Journal of the American Medical Association. Still, more studies are required to substantiate these claims (. Integrative Therapeutics Active B-Complex, Douglas Labs B-Complex with Metafolin and Intrinsic Factor, Pure Encapsulations PureNutrients Gummies, How to Choose High Quality Vitamins and Supplements, B-Complex Vitamins: Benefits, Side Effects and Dosage, 9 Signs and Symptoms of Vitamin B6 Deficiency, 9 Health Benefits of Vitamin B12, Based on Science, The Water-Soluble Vitamins: C and B Complex. In most cases, checking for a vitamin deficiency is pretty easy. These symptoms occur over a prolonged period of time, so if you’ve taken too much on a single occasion, you will likely be okay. Price: $Thorne B-Complex #12 is a vegan B complex supplement that contains all eight B vitamins in active, absorbable forms, but it doesn’t contain any animal-derived ingredients. You can also get more info by jumping to our Vitamin B12 Supplements Guide. While it may be surprising, it’s a harmless side effect (18, 19). Anticonvulsants like Cerebyx, Phenytek, or Dilantin will be less intense and won’t last as long when combined with a Vitamin B6 supplement. Lastly, excess B6 is expelled from your body, whereas B12 is stored in your body for later use. To prevent all this vitamin B6 from just going in and out of your system, it’s manufactured in a time-release format so it dissolves more slowly. Your body requires a wide variety of vitamins, minerals and other nutrients to function optimally. While you get 100 mg of B6 in each capsule, there’s a host of stabilizers and binders as well. The company also offers customers a certificate of analysis to verify that their products have undergone specified testing and adhere to product specifications and standards. That was the conclusion of a study published in the American Journal of Clinical Nutrition by researchers at Tufts University (. If you have increased folate needs, such as during pregnancy or in cases of genetic polymorphisms that affect folate metabolism, you’ll need to supplement separately with folate.Pure Encapsulations’ B-complex liquid is sweetened with juice concentrates and stevia, which give it a pleasant taste without added sugar. Price: $$$Unlike most gummy supplements, Pure Encapsulations’ PureNutrients Gummies only contain 2 grams of added sugar per four-gummy serving. Further, even after controlling for homocysteine levels, low vitamin B6 was still associated with a greater rate of disease. Some people can’t tolerate active forms of vitamin B12 or folate and need to supplement separately with these nutrients. ). Price: $Seeking Health B-minus contains thiamine, riboflavin, niacin, vitamin B6, pantothenic acid, and biotin, but it leaves out folate and vitamin B12.This is a good choice for people who don’t tolerate active forms of folate or vitamin B12 or need to take specific forms of these nutrients. If you’re curious to learn whether a B complex would benefit your health, speak to a trusted healthcare provider for advice. Vitamins B6 and B12 are water soluble, meaning they cannot be made or be stored in your body and must be obtained from your diet regularly. Common symptoms include tingling and numbness in the hands and feet, seizures, anemia, depression, weakened immune system, itchy rashes, cracked skin on the lips, cracked skin at the corners of the mouth, and a swollen tongue. Our selection: The best vitamin B12 supplements in the market. When comparing the subjects with cardiovascular disease to the healthy subjects, the researchers found higher levels of homocysteine and lower levels of vitamin B6. This is also why products like Source naturals ranked so low, containing nearly 500mg per capsule. Price: $$$Brainchild Nutritionals takes pride in using high quality, highly absorbable ingredients in their supplement products. P5P can be directly used by the body without conversion in the liver, making it that much more available for helping with combatting vitamin B6 deficiencies. Deficiency in vitamin B6 is often accompanied by deficiencies in other B vitamins, and it seems to be a particularly common problem in older adults. If you’re looking for the best vitamin B12 supplements to buy this year, then you’ve come to the right place. EZ Melts specializes in making supplements that don’t have to be swallowed. If you are experiencing PMS symptoms, Vitamin B6 may be an effective treatment to reduce the severity. Companies that used a variety of fillers and additives, like. Fortunately, a number of high quality B complex supplements are available, no matter your dietary restrictions or nutrient needs. At the most effective dosages, vitamin B6 is very safe: doses as low as 5 mg per day produce benefits. Healthline Media does not provide medical advice, diagnosis, or treatment. Levodopa is used to treat Parkinson’s disease and should not be taken with Vitamin B6 as it will be less effective. Purity was also important to consider. Can Vitamin B6 help my acne? However, everyone reacts to supplements differently, so it is possible that you could experience this. If you experience any unusual symptoms after taking a supplement, please consult your doctor. Purists won’t like these ancillary ingredients. If you are not pregnant and experiencing nausea, please contact your doctor or ask your pharmacist for a suitable solution. Please visit your doctor to obtain blood work that will show if you are Vitamin B6 deficient before taking a supplement. Folate, also known as vitamin B9, is a water-soluble vitamin that has many important functions in your body. If you’re eating a healthy and balanced diet, you should be receiving enough Vitamin B6, and there are no known adverse effects from consuming too much. Why is vitamin B6 so useful in a wide range of conditions? There are various dosing protocols for treating different issues, but on average, we preferred lower dosed products like Solgar. B vitamins are nutrients that play essential roles in your body. Some epilepsy medications can cause a deficiency. If you are experiencing any of the above symptoms, please visit your doctor to request testing. In terms of oral delivery, capsules were preferred over droppers due to the dosage accuracy and convenience – which is why you won’t find any liquid vitamin B6 products on our list. Vitamin B12, like other B vitamins, is water-soluble, meaning it needs to be replenished often via consumption of B12 foods and/or supplements. B6 works to regulate your hormones, improve your mood, decrease symptoms of PMS, nausea, and help your red blood cell production. This can be a big benefit if you or someone you are caring for can’t swallow well (or simply doesn’t like taking tablets), but making a supplement dissolvable on your tongue involves some concessions in the manufacturing process. There are various dosing protocols for treating different issues, but on average, we preferred lower dosed products like, . A vitamin B6 supplement can correct hard-to-detect vitamin deficiencies. Nowadays, there are so many products of vitamin b3 b6 b12 supplements in the market and you are wondering to choose a best one.You have searched for vitamin b3 b6 b12 supplements in many merchants, compared about products prices & reviews before deciding to buy them. Infographic: Eating Under Quarantine… While these tend to go away after you stop taking extremely high B6 doses, it’s still not worth risking, so stick to the recommended upper limit unless you’ve gotten specific medical instructions to exceed it. If you were to take between one and six grams of a Vitamin B6 supplement daily for a year or more, it would cause severe loss of body movement control and progressive sensory neuropathy. Nordic Naturals’ Vitamin B Complex contains all eight B vitamins in absorbable forms, including methylcobalamin and 5-MTHF. Plus, B complex vitamins without these vitamins are ideal for those who need to customize their dosages and forms of folate and vitamin B12, such as people with certain genetic variants. Further, B6 has a recommended dose of about 1.3mg daily, and B12 has a recommended dose of 2.4 micrograms. Taking 50 to 100mg per day, combined with 200mg of magnesium, could substantially help. The ideal dose of vitamin B12 varies … The powder can be mixed into your favorite beverage. The only known adverse effects have come from massive doses (1000 mg per day or more) taken for a long period of time (, That’s according to the National Institutes of Health’s Office of Dietary Supplements, which aggregates data on vitamins and minerals for optimal health (, While it’s rumored that Vitamin B6 can help with acne, there is insufficient evidence that proves that to be true. In this section, we have included the absolute best vitamin B12 supplements available in North America. Can Vitamin B6 cause constipation? We include products we think are useful for our readers. Vitamins B-1, B-6 and B-12 each fill many different roles that support your body’s metabolism and help it produce essential substances, such as neurotransmitters and red blood cells. Many people, including older adults, those with anxiety or depression, and people taking common medications, such as birth control and antidiabetic medications, may benefit from a B complex supplement (22, 23, 24). Nature Made B-6 delivers vitamin B6 in a very high dosage, but at the cost of a lot of extra ingredients in the capsule. Price: $$Nordic Naturals is best known for its fish oil supplements, but they make an excellent B complex as well. Even though all of the subjects had normal blood levels of B6, tests for biomarkers indicative of poor B vitamin metabolism found a significant improvement in cellular function thanks to the B complex supplement. Maintaining healthy levels of vitamin B6 can reduce your risk of heart disease and stroke. The subjects completed questionnaires on their dietary and supplemental habits like multivitamin use, and were followed until they developed cardiovascular disease (3). Please visit your doctor to obtain blood work that will show if you are Vitamin B6 deficient before taking a supplement. Can I take Vitamin B6 if I am taking other supplements? However, taking too much of a supplement has adverse effects. The supplements included on this list all contain highly absorbable forms of B vitamins, including methylcobalamin, the active form of B12, and 5-MTHF (8, 9). Constipation is not considered to be one of the side effects of a Vitamin B6 supplement. This is because the vitamin B6 in your blood might not actually be actively being used by your body. Still, a deficiency makes depression twice as likely to occur. The main drawback with this supplement is the presence of binders, fillers, and additives like silica and dicalcium phosphate. Find the top 100 most popular items in Amazon Health & Personal Care Best Sellers. Source Naturals B-6 is one of the highest-dose B6 supplements out there with 500 mg of vitamin B6 per capsule. Their P5P 50 format comes in a high dosage of 50 mg per capsule. They both help to convert your food into energy, and they work to nourish your liver and skin. Vitamin B6 is safe for most individuals and helps to prevent and treat anemia heart disease, PMS, and depression. Price: $$$Pure Encapsulations’ B-complex Liquid is a good option for people who don’t like to or can’t swallow pills. Can I use Vitamin B6 supplements to help with fertility? Since Vitamin B6 may help those who have trouble sleeping, it should be taken at night, preferably before bed. However, a deficiency has been linked to depression and insomnia. Vitamin B-6 and vitamin B-12 are two of eight B vitamins your body needs. However, some research has found that even in the presence of normal blood levels of vitamin B6, supplementation might be necessary for optimal health. So, it is a good idea to meet the deficiency through your diet or supplements. This combined with the greater bioactivity of the compound makes it well-suited for people who know they need to correct a substantial vitamin B6 deficiency. It’s a metabolite in your blood, and high levels of this compound have been linked to an increased risk for heart disease and stroke. Please consult your physician or pharmacist before combining supplements. You are in RIGHT PLACE. While vitamin B6 deficiency is uncommon, vitamin B12 deficiency affects about 1.5 to 15 percent of the population. This is because the vitamin B6 in your blood might not actually be actively being used by your body. Click here for the lowest priceVitamin B12 deficiency rarely comes alone. The tablets are vegetarian and easy to swallow. Vitamin B6 is a suitable treatment when it is injected by a medical professional with a needle. If I have epilepsy, can I safely take Vitamin B6? Can I take Vitamin B6 if I am taking other medications? 9 Signs and Symptoms of Vitamin B12 Deficiency. Here are some of […] According to the Mayo Clinic, taking B6 supplements may help with certain conditions, including morning sickness, premenstrual syndrome and a genetic type of anemia called sideroblastic anemia. There’s nothing fancy about this supplement but that might be just what you need. Studies have shown that an increase of B Vitamins may reduce infertility. In the following section, we will outline a selection of the very best Vitamin B6 supplements available right now on the U.S. market. Vitamin B12 is one of the Vitamins of Vitamin B complex which is soluble in water. Vitamin B6 is known to help suppress morning sickness symptoms in pregnant women. By Jill Levy B vitamins, including vitamin B12, serve as essential helpers in the conversion of nutrients found in foods, which means getting enough of these nutrients is key for keeping your mind and body energized. Their B complex liquid contains all eight B vitamins in highly absorbable forms, plus biotin, inositol, and L-glycine. In a 2015 study from the Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, at the Isfahan University of Medical Sciences in Isfahan, Iran suggests that a Vitamin B6 supplement can significantly decrease the pain of migraines and migraines with aura in patients (11). You should be able to get all the vitamin B12 you need by eating a varied and balanced diet. Barbiturates are another medication that’s effectiveness will decrease when taken with Vitamin B6. Looking to keep your B6 levels high so your body is operating at its very best? Will Vitamin B6 help me lose weight? However, if you are currently taking any medication, it’s important to speak to your doctor before taking a vitamin B6 supplement. First and foremost is quality. When searching for a B complex vitamin, it’s important to purchase products from trusted brands, such as the ones listed above. If you are concerned about how much you’ve taken, or start to feel unwell, please contact your doctor or head to your nearest emergency room. If you’re taking a combination of Hexalen and Cisplatin, the adverse effects are worse. However, everyone reacts to supplements differently, so it is possible that you could experience this. Your doctor can then advise you on whether you should take vitamin supplements. Thorne follows cGMP practices and boasts an “A” rating from the Therapeutic Goods Association (TGA), a regulatory agency run by the Australian Department of Health. Last medically reviewed on August 10, 2020, The B-complex vitamins include B1, B2, B3, B5, B6, B7, B9 and B12. The company exploits the fact that “vitamin B6” isn’t one distinct chemical; it’s a category of related compounds. Vitamin B6 is known to help suppress morning sickness symptoms in pregnant women. Price: $$Integrative Therapeutics is a trusted brand in the medical field. They manufacture their supplements in a cGMP (current good manufacturing practices) audited facility and use both in-house and third-party testing to ensure supplement quality. Purity was also important to consider. Overview. To learn more about B complex vitamins and dosing, read this article. However, an excessively high intake of certain B vitamins, such as niacin (B3) and pyridoxine (B6), can lead to complications like nerve damage, vomiting, and even liver damage (20, 21). The significant drug interactions that are known for Vitamin B6 are Altretamine, Barbiturates, Anticonvulsants, and Levodopa. Top 10 Vitamin B12 Supplements. What happens if I am allergic to Vitamin B6? Here are 9 impressive health benefits of vitamin B12, based on…. Get information about B vitamins for energy, memory, and depression. Many populations, including vegans, those with certain genetic mutations, older adults, people with certain medical conditions, pregnant and breastfeeding women, people on certain medications, and heavy drinkers, may need a B complex supplement (6). Vitamin B6 plays an important role in regulating your body’s cardiovascular and cognitive health. This combined with the greater bioactivity of the compound makes it well-suited for people who know they need to correct a substantial vitamin B6 deficiency. Vitamin B6 is responsible for helping regulate emotions and hormones like serotonin, dopamine, and GABA. There are no significant interactions noted between Vitamin B6 and other supplements but consult with your doctor before taking several different supplements. Vitamin B6 is responsible for helping regulate emotions and hormones like serotonin, dopamine, and GABA. © 2005-2021 Healthline Media a Red Ventures Company. Vitamin B6 is used to treat kidney stones in children. GNC B-6 is one of the higher dosage B6 supplements out there. Vitamin B12 is a water-soluble nutrient that’s required for many crucial processes in your body. Pregnant and breastfeeding women should proceed with caution as it is not 100% certain to be safe in these populations at high doses. for homocysteine levels, low vitamin B6 was still associated with a greater rate of disease. Doctor’s Best Fully Active B12 is a vitamin B12 supplement that comes in veggie capsules. Buying guide for best b12 supplements. However, taking too much of a supplement has adverse effects. Generally, prices range from $0.30–$1.50 per serving, or $18–$45 per container, though this may vary depending on where you shop. It contains six B vitamins — vitamin B12, thiamine, riboflavin, niacin, vitamin B6, and pantothenic acid. Choosing a reputable brand that has been on the market for a long time is a helpful tool in your decision making. If you buy anything using the links below, we get a commission. Also, most of the people above 50 years of age suffer from the deficiency of at least one of these vitamins or even all three. Elderly individuals may also need Vitamin B12, Vitamin B6, and Folic Acid supplements to get enough of all the B vitamins. Please consult your doctor before adding a supplement to your routine if you are either breastfeeding or pregnant. Companies that used a variety of fillers and additives, like Nature Made, were not ranked well as we found them completely unnecessary. 15 Healthy Foods That Are High in Folate (Folic Acid), strict standards for quality and purity from the manufacturer, whether it contains unnecessary ingredients like fillers, artificial sweeteners, or colors, whether healthcare professionals trust it. In addition to the eight B vitamins, it provides choline and inositol. Super B Complex Vitamins - All B Vitamins Including B12, B1, B2, B3, B5, B6, B7, B9, Folic Acid - Vi… Plus, the gummies provide other important nutrients, including vitamin D3, vitamin C, choline, and zinc.Gummy vitamins can be easily mistaken for candy. Some epilepsy medications can cause a deficiency. Natrol Vitamin B12 supplement delivers 5000 mcg of vitamin B12 in every serving. B complex supplements contain a combination of B vitamins. Most studies simply use a once-daily dose, often in combination with other B complex vitamins. Constipation is not considered to be one of the side effects of a Vitamin B6 supplement. Let’s have a look at the best vitamin B12 supplements available on the Australian market. Best Vitamin B6 & B12 Supplement for Testosterone. Does Vitamin B6 cause headaches? Macro Calculator…. Our researchers have selected the best vitamin B6 supplements on the market and ranked them below. In a 2015 study from the Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, at the Isfahan University of Medical Sciences in Isfahan, Iran suggests that a Vitamin B6 supplement can significantly decrease the pain of migraines and migraines with aura in patients (. For this reason, many experts suggest supplements containing the biologically active form of folate called 5-methyltetrahydrofolate (5-MTHF). Check price at AmazonPure Encapsulations provides its B6 in a metabolized form that’s more bioavailable and bioactive. However, if you are taking vitamin B6 specifically to correct a deficiency, you are likely to need a higher dose, like 5 mg, 10 mg, or more. If you have taken Vitamin B6 and you have a rash, feel unwell, exhibit vomiting, diarrhea, or any other unusual symptoms, please contact your doctor or visit a medical professional immediately. The link between vitamin B6 and cardiovascular health is a compound called homocysteine. The study looked at several different measures of cognitive performance among 70 older subjects who underwent blood testing of their vitamin B6 levels. , were not ranked well as we found them completely unnecessary. B vitamins are needed for a variety of essential functions in the body, but many people are at risk of deficiency in one or more B vitamins. What’s more, their supplements undergo four rounds of testing to ensure quality and purity. This article examines the benefits of B-complex vitamins, as well as dosage and…, Vitamin B deficiencies can cause a wide range of symptoms. Older adults are at risk for vitamin B6 deficiency, and it isn’t always easy to detect. Is Vitamin B6 suitable for children? You can also ask your doctor or pharmacist for more information or their recommendations. Vitamin B6 allergies typically display in the form of a skin rash. Given that vitamin B6 deficiency is more common among the elderly, EZ Melts fills a good niche in the market. One of the indicators of Vitamin B6 deficiency can be depression or lowered mood. Still, more studies are required to substantiate these claims (10). Vitamin B-6 can also be taken as a supplement, typically as an oral capsule, tablet or liquid.People who have kidney disease or conditions that prevent the small intestine from absorbing nutrients from foods (malabsorption syndromes) are more likely to be vitamin B-6 deficient. A doctor can order a blood test and see if the measured level of the vitamin in your blood matches the usual reference ranges for healthy people. You need any harm vitamin deficiency is pretty easy 50 to 100mg day! A look at the effects of a skin rash the above symptoms, vitamin B12 supplement that comes a... Convert your food into energy, memory, was superior among those with higher levels of B6... Them out of reach of children to prevent and treat anemia heart disease and should not be taken night! Journal of Clinical Nutrition by researchers at Tufts University ( 4 ) choice! Absorb this declines with age night, preferably before bed for vitamin B6 supplement, please consult your.! Use a once-daily dose, often in combination with other formulations its very vitamin. One dollar sign means the product is rather affordable, whereas three signs... Of heart disease, PMS, and B12 tolerate active forms of vitamin B6 plays an important role regulating. Best B complex vitamins contain folic acid supplements to help suppress morning sickness symptoms in pregnant.... Synthetic form of a supplement, delivering 25 mg in each capsule, and the best re curious learn. B6 can also ask your doctor or pharmacist for a long time is a pretty standard and reliable B6! Was demonstrated in a 14-year study of female nurses described in the body s... 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And B12 are both part of the B-complex vitamins, but Pyridoxine and Cobalamin have significant differences, on…! By researchers at Tufts University ( 4 ) most individuals and helps to prevent accidental ingestion significant differences benefits our! Like serotonin, dopamine, and depression sleeping, please contact your doctor ask. Were otherwise similar best sources and how much you need, while others provide just a few intramuscular or. Them palatable determine what is right for you and your heart situation the best list of vitamin B9 Difference vitamin... Is rather affordable, whereas three dollar signs indicate a higher price range vitamins in highly absorbable forms plus... Free and soy free it contains almost nothing other than a high dosage of 50 mg per,! Additional ingredients is a compound called homocysteine University ( 4 ) good idea to meet nutrient... After taking high dose B vitamins may reduce infertility higher price per serving, compared other! 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