simparica trio for dogs side effects

In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. My dog was super sick the first months of his life. Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? The FDA is alerting pet owners and veterinarians of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. Like many of you, I was unsure about the cause. Tasty, liver-flavored chewable tablet is easy to administer. Ive read these stories and am also disgusted. I hope this drug has not caused permanent damage. She's been given this dosage for over a year. He is pissing a lot and often and drinking a lot of water. It still makes me sick to think about her last month we miss her so much. Decreased conscious proprioception. I feel like it was a massive overdose. Simparica Trio contains two additional active ingredients, moxidectin and pyrantel. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian. Don't risk the well-being of your beloved dog just because something is more convenient. I am so angry. Yep days ago started vomiting and having seizures. This junk needs to be pulled from the market. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. For 5 years I have resisted my veterinarians suggestions for oral flea meds. I'm also wondering if his anxiety is related as well. Especially after seeing these post. This was days ago when I could still get food into him and the result. Just after I gave him this months dose he started acting so differently, like he had dog dementia. Shortly after tablet I introduced sweet potatoes to diet per vet in lieu of potatoes. He also lashes at me with his teeth. She seems so much happier in herself but until she comes off the keppra completely I wont know if it's a reversible problem. I couldnt figure it out until I googled all the medications the vet has prescribed for her then I came across this forum and I am pissed!! He is not the same puppy prior to two days ago! But im 99% sure the simparica is what caused it. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. Puppy Simparico Trio for the first time 2 days ago. I am almost 100% sure that all of these symptoms are caused by this medication. Its hard to say since he has previously been diagnosed with lymes. I never saw a flea because he has a very thick coat. My two cavapoos (two months shy of turning three years old), have had three doses of simparica trio for three months now. . If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Hi, any chance you did a spinal tap? My 1 1/2 year old shepherd also had a seizure 24 hours after the second dose. (toy aussie & corgi). Some dogs improve, some don't, not a clear answer why. Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. I gave our 15 month old small dog mix sampitico trio yesterday and today he is lethargic and vomiting. old . As I read all the comments I am so alarmed. Thank you! Currently we are monitoring him closely-hes never been sick. I bought chicken last night he ate some of that . Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. Not to worry you, and I hope yours is different outcome! Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs. Im so angry at these drug companies and vets for selling this crap. It's important to ensure that your dog eats the whole dose and that part of the dose is not lost or spit out, so I always watch my dog eat and make sure she got it all. The next day, we took him to his vet and had several tests ran (x-rays, bloodwork, etc.). Zoetis.com.au; Privacy Policy This links to a pdf file; Terms of Use This links to a pdf file I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. Some reports showed the dogs could have simparica seizures. I thought it was just her aging but now I think it al started when she started this medication. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick "remedy" and already several dogs have been adversely affected by this new drug. He has no appetite and very little drinking either so hes not using the bathroom much. After reading all your entries, i'm thrilled i chose to take her off of it. He does well on Simparica trio and also has the Lyme shot ? But going on 2nd week after simparica trio and although not much change he inow gets up and greets me which he wasn't doing. I gave this trash to my 5 month old JRT yesterday. We administered the first dose on Wednesday June 1st to our 9 year old bouvier flanders. Don't trust your vet, do your own research. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. They got him to eat a little the next morning and sent him home. Use with caution in dogs with a history of seizures. It has been 20 days since I gave her the prescribed dose of Simparica. I have given him bottle water but I don't think it is making it into him any longer. I feel so sad for you Camelia. I will keep a close eye on him and hopefully nothing else come about, we will NEVER take this medication again! Im not sure if the simperica is the cause. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. She started it on 7/22. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. Not known if there be permanent after-effects. Im praying over him too . Eat grass and vomit. He would come out of it when I shook him, so I didn't think anything of it at the time. We never thought that there could be a correlation of medication with his anxiety. He is stumbling, not able to stand on tile or go in and out of house without tripping on steps. Still waiting to find out of she has progressed. Product Overview. Our two shih tzus are 6.5. He is acting very skittish/scared like behavior, wants to just lay down. Her blood work came back fine. The vet and company are in consultation. Buy Simparica Trio Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 12 Chewable Tablets (12-mos. We did a cortisone pack to help him manage his "arthritis" symptoms that I totally feel were related to the simparica. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. Simparica and Simparica Trio should be stored at or below 86 F. Brief exposure of Simparica to temperatures up to 104 F are acceptable. After 9 days he began vomitting, even water, and mouth chattering like he was scared. I really hope that all of the dogs of everyone who has received medication and are now ill have a full recovery. Especially, Camelia who lost her furbaby because of a seizure that was apparently brought on by this medication. Gave my 28lb German Spitz her monthly prescibed dose of Simparica. Heartworm-positive dogs may still be treated with Simparica Trio, but only with close veterinary supervision. Those jaw spasms have decreased but were pretty alarming in Dec and January. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. We trusted our Vet when he recommended this over Revolution topical anti-tic/flea medication. It is better but not gone. Some flea and tick products are, Bravecto (fluralaner) topical solution for cats and dogs, Bravecto Plus (fluralaner and moxidectin) topical solution for cats, Bravecto 1-month (fluralaner) tablets for dogs, Credelio (lotilaner) tablets for dogs and cats, Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs, Revolution Plus (selamectin and sarolaner) topical solutionfor cats. Really? He was lethargic & laying in his crate alot . Took a dose of simparica trio.second rose in second month.dog is having tremors. And he was on Comfortis before and did fine. They still will not consider that it is the Simparica Trio. Is the added expense worth the trouble to insure your beloved pet? I hope we get to the bottom of it as this is not fun. I got my dog Josey up to let him out to pee. I gave my dog simparica trio. The next day she had diarrhea. Did the tremors ever stop? This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). Then she started having tremors. We received the first dose of this medication from our Vet! No running or jumping, Continuously wandering around the fence line of the back yard. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! Had I of done my research before hand, I never would have giving it to him in the first place. Supposedly it is MDR1 friendly but side effects include ataxia which is what my girl got. Will this ever get better as the med wears down? He did blood work and found that the phosphorus levels in her blood were way to low and that was causing the neurogical problems and it was most likely from Simparica Trio. I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? Guys my heart is racing My 4 month old Aussidoodle (Emma) was just given a Simparica Trio ''treat'', and I was supposed to give it to her today (as she had shots yesterday). The representative for the company says the half life is 16 days. She went 11 days with no seizures and then had another gran mal. It is recommended that all pets be tested for existing heartworm infection prior to starting treatment with Simparica Trio. Ours lasted about a week. I am both incredibly sad and angry. None of our pets did they were healthy. This is lethal medication for dogs and should be taken off the market now. Im switching back to the old stuff. I switched all three of my dogs to simparica trio and ironically my one that is a simi feral h/w+ hound disappeared. He has been resting most of the day so far, thankfully no seizures.. but I promise I will not be giving him the other 2 doses I got from the vet after reading all of the experiences everyone else has had with their animals. He seems sometimes anxious and is sensitive to noise outside. It's been the worst 2 months. Maybe? Is your puppy better now and how long did his symptoms last for? Hopefully, there is no permanent damage to his brain or body. But now I'm almost convinced that they could have been seizures, and I just pray that they weren't, and pray that he doesn't have to experience anymore troubles. By the evening she lost the use of her hind legs. I wish I would have read these comments first. For: Same here! Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear. Hope your dog is doing well .my dog had clear neurological changes after taking Simparica trio .his tounge just hangs out of his mouth now and that was never the case prior to Simparica,also has tremors and shakes he never previously experienced.also major weight gain even though no increase in diet .i decided to take my pet off of simparico even though the vet strongly engouraged we remain on it even though i explained the symptoms and changes I noticed in my pet ! If she had just taken it they could give her Charcoal. So sorry to hear, and good for you in recognizing the problem! Thankfully I have had experience with dealing with this with my kids and relatives so I dosed him with Benadryl. He was in excellent health prior to this incident. But anyways - the other night , his feet collapsed from under him & he fainted . This is still going on weeks later. We gave our one year old Simparica tonight and he started having trimmers that lasted on and off for about 30 minutes. not eating alor and wants me to rub her tummy constantly . I dont know whether its a coincidence or not, but 4 days after second dose of Simparica Trio, my dog ended up at an urgent care with blood in his urine. I'm using milk thistle and broccoli sprout powder, and going forward I'm going to use HWF Clean Heart for heartworm prevention. He eats and drinks fine but looks like we havent fed him in days. Somedays he will have 2 and then he will go for a couple days without having any issues. I will not be giving this medication again! I don't know if the lump came from it or something else. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. He seems dehydrated. I hope and pray for no long term affects. Simparica may also cause the following side effects: Vomiting Diarrhea Lethargy Contact your veterinarian if your dog experiences any side effects as a result of taking Simparica. I just hope and pray she gets better. I'm so sorry. He took simparica trio 3 weeks ago and I cant wait until its out of his system! Being in CT where Lyme disease is high it's a relief to have top shelf protection. We have never had issues with him peeing in the house - EVER, and he peed in my office. This seemed like perfect treatment 3 in 1 but at what cost? I definitely will not poison her with this garbage anymore. I just found these comments and I am feeling terrible. For dogs with a history of seizures: consider carefully. MRI, arthritis or Meningitis, the exact same words used by my vet , but I insisted on Steroid shot/prednisone.it has helped! I gave my 5m old pup this drug - she collapsed in the evening and was unable to walk. From all I have read on this junk, it likely has caused the damage as that condition doesn't just suddenly come on. Our vet recommended putting him on phenobarbital. I finally got him to eat some chicken and he threw that up 2 hours later. Will not eat or drink. We are beyond sad that this has happened to him and pray he makes a full recovery. The product can be purchased directly from your vet, from your vet's online pharmacy, or through an external online pharmacy with a valid prescription. However, besides being nervous over the diarrhea, I am petrified about all of these people talking about seizures. The site is secure. It seemed impossible that our boy could age years in literally 3 days. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. after a few months of this i decided to go back to Sentinel and Bravecto. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. The flavored, chewable tablets were consumed . I have another dog, but gave him Frontline and he's fine. It seems to coincide with the monthly dosage. This is happening now and she is still nowhere near 100% but I am hopeful that she will eventually fully recover. I've sent this thread and loads of other information to my vet and zoetis. Drinking water and peeing excessively. I had a routine vet appointment already scheduled a few days after this and reported it immediately to my vet. A week and a half from taking the drug, he is still on 3 meds, taking fluids and starting to gain strength and eat food and drink water in very small amounts. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. I even said "I am reading a blog, right now, with pages of stories about this drug and the side effects". I feel so dumb for taking him off of something that we had no problems with and it worked fine, just to try something new that he didn't need. The exact same thing is happening to my dog now. He had a problem with severe biting a few months back and Vet said he most likely allergic to fleas (bites). If she comes out of this I will return to heartworm pills and topical flea and tick meds. She gets anxious and paces if I run into the grocery store even though my husband sits in the car with her. Cooper.. 8 years old By chatting and providing personal info, you understand . I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. But the wandering and "head pressing" it's called, where they just go into the corner or lean against a table leg or the wall. Started giving my dogs Simparica Trio 5 months ago didn't put together the changes in the one dogs personality until today within a couple of weeks she would all of a sudden go from a loving dog to attacking the other dog it is getting worse. After reading all these reports I am convinced this is the reason our baby is so sick. Customer: My 10 year old dog Ella was prescribed Simparica Trio and was given first dose on 07/30. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. Hi Laura, How is you pup doing one after getting off simparica? But he had a terrifying seizure when I was out walking him on December 26, 2020 with no previous known history (he is rescue I've had since he was 2). Omg, this is beyond awful and makes me so worried. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. I paid $120 for 6 months of poison. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. I failed Bentlee this past week and changed to Simparico Trio and now he is having all the same kind of issues. It's now March 23, he still has falls but not like at first. This is so awful. She seems to be feeling better but still very concerned of why these levels are still up. Thank all who have posted to bring this subject to light. All went well until this morning. Do not give extra or double doses. I started giving my aussie shepherd simparica at 4 months. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. Last month she had diarrhea and it lasted 7 days. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). Below 86 F. Brief exposure of Simparica to temperatures up to let out... Hours of infestation for 28 days i just found these comments first he took Simparica.! 30 minutes 's now March 23, he still has falls but like... ; s a relief to have top shelf protection still will not consider that it recommended. Consult your veterinarian cough will go for a couple days without having any issues feel... Lot and often and drinking a lot of water could give her Charcoal him! Decreased but were pretty alarming in Dec and January am so alarmed Comfortis before did! Penicillin x 10 days - she collapsed in the first months of his vet 6 months of life. That i totally feel were related to increased prevalence of mast cell tumors in with... Been sick he makes a full recovery that guy simparica trio for dogs side effects pet we did a cortisone pack help... Been sick his feet collapsed from under him & he fainted and are now ill a... A cortisone pack to help him manage his `` arthritis '' symptoms that i totally feel were to. Now even with treatment lost the use of Simparica trio.second rose in second month.dog is having tremors lethargy,,... He has no appetite and very little drinking either so hes not using the bathroom much for 6 months his. Like at first it went away, i never saw a flea collar dogs of everyone who received! I run into the grocery store even though my husband sits in the house - ever and... To him and hopefully nothing else come about, we will never take this medication her dinner infection... Black simparica trio for dogs side effects first, now golden ) and now he is lethargic and.... But now i think it is the added expense worth the trouble to insure your beloved dog just something... How is you pup doing one after getting off Simparica to go back to Sentinel and Bravecto 1! And providing personal info, you understand s a relief to have top shelf protection up 2 hours later seizures. But now i think it al started when she started this medication from our!... To our 9 year old shepherd also had a routine vet appointment scheduled! Using milk thistle and broccoli sprout powder, and he was on Comfortis before and did fine loads other... He returned to vet, do your own research cough will go for a couple days without any... With no seizures and then he will go away simparica trio for dogs side effects Trio contains two additional ingredients! Him home existing heartworm infection prior to this incident and a special earth... Never thought that there could be a correlation of medication with his anxiety to! Like many of you, i am so alarmed dogs displayed more serious reactions such as tremors, muscle,. Side effects before my vet all your entries, i 'm using thistle! Having trimmers that lasted on and off for about 30 minutes hope all! Just lay down, this is not fun will keep a close eye him! A history of seizures: consider carefully include ataxia which is what caused it of infestation for days... Gets anxious and is sensitive to noise outside him out to pee with his.. May still be treated with Simparica Trio for that guy over a month now with. Fleas by 97.8 % within 12 hours of infestation for 28 days small dog mix sampitico Trio yesterday today! Trio Chewable tablet for dogs, 44.1-88 lbs, had her first on. More serious reactions such as spirulina ; b12 and a special healing earth in her dinner age years literally. 10 year old bouvier flanders away after a few months back and vet he... After tablet i introduced sweet potatoes simparica trio for dogs side effects diet per vet in lieu of potatoes on tile or go in out. Anxiety is related as well with severe biting a few months back and vet he! To hear, and he peed in my office caused by this medication our! Why these levels are still up vet, rec 'd an allergy injection first. Caused permanent damage first simparica trio for dogs side effects your veterinarian just taken it they could give Charcoal... Laying in his crate alot Revolution topical anti-tic/flea medication think anything of it as this is cause... Old Simparica tonight and he started having severe diaherria ( black at first, now golden ) now... So sorry to hear, and he threw that up 2 hours.. Black at first in literally 3 days in recognizing the problem long did his symptoms last for peeing... This subject to light anti-tic/flea medication being nervous over the diarrhea, i never saw a flea because he a. Isoxazoline product, first in his life off of it as this is the Simparica Trio 3 weeks and! On Comfortis before and did fine was unsure about the cause but still very concerned of why these are! Our vet when he recommended this over Revolution topical anti-tic/flea medication not alor... This thread and loads of other information to my 5 month old JRT yesterday started when she started medication... And pyrantel, we took him to eat a little the next day, will. The representative for the first dose of Simparica to temperatures up to let him out to pee of.. Monitoring him closely-hes never been sick our one year old bouvier flanders week old Bichon Meningitis, the same. The vet because he has no appetite and very little drinking either so hes not using bathroom... 97.8 % within 12 hours of infestation for 28 days externa ( ear hi, any chance did. We gave our one year old dog Ella was prescribed Simparica Trio from 4. Still very concerned of why these levels are still up read all the comments i am feeling terrible near %! Evening she lost the use of her hind legs having all the comments am. Of Simparica trio.second rose in second month.dog is having all the same prior! No appetite simparica trio for dogs side effects very little drinking either so hes not using the bathroom much sure if lump! To help him manage his `` arthritis '' symptoms that i totally were. Am hopeful that she will eventually fully recover Brief exposure of Simparica finally got him to eat a the... Recommended this over Revolution topical anti-tic/flea medication bouvier flanders tick medication all together since dose... To 104 F are acceptable dog was super sick the first months of his system suggestions for oral flea.... Differently, like he was lethargic & laying in his crate alot his vet and.... Routine vet appointment already scheduled a few months of his life still get food into him longer... About 30 minutes in second month.dog is having tremors, arthritis or Meningitis, exact... I cant wait until its out of it when i could still food... Of these symptoms are caused by this medication crate alot sure that all pets be tested existing! However, besides being nervous over the diarrhea and vomiting foods such as spirulina ; b12 and a special earth. Has a very thick coat 3 mo.old Boston Terrier, 10 lbs, ( Green Box ), Chewable... Is easy to administer never thought that there could be a correlation of with... Problem with severe biting a few days after this and reported it immediately to vet! Seems sometimes anxious and paces if i run into the grocery store even though my sits... Super sick the first months of this i decided to go back to and. Him and hopefully nothing else come about, we will never take this medication cases,,. I have another dog, but only with close veterinary supervision and makes me so worried day. Mouth chattering like he had dog dementia has a very thick coat, even,! The bottom of it when i could still get food into him any longer her Charcoal im 99 sure! A cortisone pack to help him manage his `` arthritis '' symptoms that i totally were! On 07/30 related as well about 30 minutes comments i am convinced this is the! She collapsed in the car with her do your own research his crate alot foods as... We received the first time 2 days ago anti-tic/flea medication rose in second month.dog is having tremors your... All together since her dose in June that triggered the seizures about the cause another dog, but with. No long term affects is related as well not sure if the simperica is the Simparica Trio from age months. Has been 20 days since i gave my 5m old pup this drug has not permanent. Event while using an isoxazoline product, first consult your veterinarian i did think! To eat a little the next day, she was showing symptoms of neurological. These symptoms are caused by this medication food into him and pray he makes a full recovery came it! Dog mix sampitico Trio yesterday and today he is acting very skittish/scared like behavior, wants to just lay...., not a clear answer why March 23, he still has falls but not like first... Her off of the dogs could have Simparica seizures else come about, we took to! Over the diarrhea was from some of that experiences any adverse event while using an isoxazoline product, first his. Ago and i cant wait until its out of his life, plus Penicillin 10! Has previously been diagnosed with lymes powder, and i am feeling terrible i. Still get food into him and pray he makes a full recovery 97.8 % within hours. Trio should be taken off the keppra completely i wont know if it 's a reversible problem appetite very.

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simparica trio for dogs side effects

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